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Cellular Dynamics.jpg

Cellular Dynamics公司可以大规模从干细胞诱导分化生产人类细胞,用于基础研究,药物发现和再生医学应用。CDI提供了几种末分化的细胞种类作为目录产品:iCell心肌细胞,iCell神经元,iCell内皮细胞和iCell肝细胞。 CDI的MyCell®产品组合能够为客户提供的供体样品进行重编程,基因编辑和分化。该公司还有几种来源于多能干细胞的原型产品,包括iCell心脏祖细胞,iCell造血祖细胞,iCell星形胶质细胞和iCell骨骼成肌细胞等。

 

Fujifilm, once a Company whose core business was photographic film, has diversified and strengthened its portfolio based on developing or acquiring proprietary technologies as well as a deeply held corporate philosophy of enhancing the quality of human lives worldwide. One key area of focus for the Company is Healthcare, and Fujifilm acquired Cellular Dynamics International in May 2015, renamed it to FUJIFILM Cellular Dynamics, Inc.(FCDI) in 2018 to drive innovation in this business area. We see great potential in FCDI as a key component in our mission to be the global leader in regenerative medicine and drug discovery through cutting-edge science and technology.

 

To date FCDI has already achieved leadership in the induced pluripotent stem cell (iPSC) field as one of the only companies in the world to industrially manufacture human cells derived from iPSCs with high quality, purity, and reproducibility and in virtually unlimited quantities. Not only have we achieved this across multiple healthy and diseased donors for the research market but also, we have begun to manufacture human cells under cGMP conditions – a requirement as these human cellular products move from a tool used in drug discovery into a therapy used in regenerative medicine applications.

 

Cellular Dynamics公司的主要产品包括:

iCell Cardiomyocytes

iCell Cardiac Progenitor Cells

iCell Neurons

iCell Astrocytes

iCell DopaNeurons

iCell Hepatocytes 2.0

iCell Hepatoblasts

iCell Skeletal Myoblasts

iCell Endothelial Cells

iCell Hematopoietic Progenitor Cells

iCell Macrophages

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Tocris Bioscience.png

Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌,其产品也广为各大药厂、大学、研究机构,超过五万名科学研究者所采用。 目前,產品內容已超過一千六百種以上,並每年持續不斷的增加新的產品。目前,产品内容已超过一千六百种以上,并每年持续不断的增加新的产品。

 

Tocris bioscience是位于英国布里斯托尔(Bristol)的高品质试剂提供商,共有2000多种产品,主要集中在神经科学和信号传导领域,产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等,主要产品包括GPCR ligands,神经传递素,离子通道调控剂,信号通路抑制剂等,这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者,其生产的影响神经系统的化学物质被多次引用,这些物质很多都来自Jeff Watkins(Tocris 的创立人)在Bristol大学原创性的研究工作。

 

Tocris Bioscience的主要产品包括:

Small Molecules

Peptides

Aptamers

Controlled Substances

Compound Libraries

DREADD Ligands

Fluorescent Imaging

Ligand Sets

Optopharmacology

Reagents

Toxins

 

按照研究领域细分:

Cancer

Cardiovascular System

Endocrinology

Immunology

Neuroscience

Pain & Inflammation

Respiratory System

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Allele Biotechnology.jpg

Allele Biotechnology位于美国圣地亚哥市,主要专注于对生物过程的机制进行探索,以开发生物医学及治疗相关的技术和产品。以各个物种的iPS细胞、人类cGMP iPS细胞及衍生的细胞为材料,Allele Biotechnology利用专利性的非整合细胞编辑方法,开发了出了细胞治疗和药物筛选的技术。Allele Biotechnology具有深厚的基因组修饰和细胞荧光报告因子的经验,为客户提供优异的细胞检测解决方案。Allele Biotechnology还提供荧光蛋白、高效荧光素酶底物、基因分型试剂盒、骆驼抗体等产品;此外还在RNA干扰领域尤其独特的专利。

 

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for biomedical research and therapy development.

 

Our mission is to increase accessibility to innovative molecular biology research tools by offering cutting edge technologies in individual products and fully integrated platforms. Allele utilizes proprietary non-integrating cellular reprogramming methods to develop cell therapy and enable drug discovery through the use of human and non-human primate iPS cells, cGMP-grade human iPS cells and their derivatives. With additional expertise in genome modification and unique cell-based fluorescence sensors/reporters, Allele provides advanced cell and assay development solutions. Allele also has developed a wide variety of advanced research tools including superior fluorescent proteins, highly efficient luciferase assay substrates, genotyping kits, and camelid antibodies that have been validated for co-immunoprecipitation, histology, and flow cytometry. The Company has also been a leader in the RNAi field with its patents in Pol III promoter-driven siRNA, shRNA, and miRNA.

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