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Toronto Research Chemicals.jpg

Toronto Research Chemical建立于1982年,致力于为生物医药研发人员提供小分子有机物,库存超过57000种,并通过一系列方法保证标准物质的纯度。

 

Toronto Research Chemicals, TRC, was founded in 1982 by Dr. David Dime to manufacture and supply researchers in the biomedical fields with specialized complex organic small molecules that were not commercially available. In 1983, the company was incorporated in Ontario as Toronto Research Chemicals Inc. It was initially located at the University of Toronto. As the business expanded, larger facilities were required to accommodate the growth.

 

Today, Toronto Research Chemicals Inc. employs about 150 full time staff, of which approximately 80 are PHD's, operating in a 65,000 square foot facility. TRC, currently manufactures and distributes in excess of 33,000 products to more than 65 countries.

 

Toronto Research Chemical的产品涵盖:

Activators; Affinity Chromatography; Agonists; Agro-Products; Aldehyde Labeling Reagents; Aldehydes; Amines; Amino Acids & Derivatives; Anti-virals; Antibiotics; Apoptosis; Benzodiazepines; Biotin Derivatives; Boron Derivatives; Carbohydrates; Catalysts; Charged Bifunctional Reagents; Charged Monofunctional Reagents; Chelating Agents & Ligands; Chiral Reagents; Chromatography Media; Cross Linking Reagents; Crosslinker; CyanineDyes; Detergents; Diagnostics; Dihydropyridine; Dopamines; DrugAnalogues; ElectrophoresisMaterials; Environmental; Enzyme Substrates; Ephedrines; Fatty Acids & Derivatives; Fentanyls; Fluorescent Labels &Indicators; Glucuronides; Glutathione S-Transferase Agents; Glycerols; Glycosidase Inhibitors; Heterocycles; Hydantoins; Impurities; Indole Derivatives; Inhibitors; Inositols; Isotope Labelled Compounds; Labeling and Diagnostics Reagents; Lipids; Lysergic Acid and Derivatives; Maleimide Derivatives; Mercaptans/Thiols; Metabolites; Methadones and Analogues; Miscellaneous Compounds; Morphine Based Alkaloids; MTS & Sulfhydryl Active Compounds; Mutagenesis Research Chemicals; Neurochemicals; Neutral Bifunctional Reagents; Neutral Monofunctional Reagents; Nicotine Derivatives; Nitric Oxide Reagents; Non-nucleoside Reverse Transcriptase; Nucleotides; Oligosaccharides; Opium Alkaloids - Natural and Derivatives; Peptides; Pharmaceuticals; Phenethylamines; Phosphorylating and Phosphitylating Agents; Phosphorylcholine Derivatives; Photoaffinity Labels; Polyethyleneglycol Derivatives; Polymers; Protein Kinase Inhibitors and Activators; Pyridyl Disulfides; Retinoids; Selenium Compounds; Sphingosine Derivatives; Spin Labeling Compounds; Steroids; Sulfonyl Chlorides; Tyrosine Kinase Inhibitors; Wittig Reagents.

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更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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Toronto Research Chemicals
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Zymo Research.jpg

Zymo Research公司位于美国加州Orange County,创建于上世纪90年代初,主要研发和生产生物实验室使用的各种试剂、耗材、仪器。其DNA提取试剂盒系列产品以“快速、简便、超纯”的特点在众多生物科技产品中脱颖而出,独占鳌头。已经形成了覆盖美、英、德、法、日、韩等50多个国家的销售网络,销售额快速增长。使用其产品的实验论文在各种权威性科技期刊(NATURE 自然、PNAS 美国科学院院刊、StemCells 干细胞、Nucleic Acids Res核酸研究等)上发表。

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艾美捷科技代理Zymo Research全系列产品,产品列表如下:


产品名称产品编号
Quick-DNA  Miniprep Plus KitD4068T / D4068 / D4069
Quick-DNA MiniprepD3024 / D3025
Quick-DNA Microprep KitD3020 / D3021
Quick-DNA 96 KitD3010 / D3011 / D3012
Quick-DNA Microprep Plus KitD4074
Quick-DNA Midiprep Plus KitD4075
Quick-DNA Magbead Plus KitD4081 / D4082
Quick-DNA  96 Plus KitD4070 / D4071
ZymoPURE II Plasmid Midiprep KitD4200 / D4201
ZymoPURE II Plasmid Maxiprep KitD4202 / D4203
ZymoPURE Plasmid Miniprep KitD4208T / D4209 / D4210 / D4211 / D4212
ZymoPURE - Express Plasmid Midiprep KitD4213
ZymoPURE II Plasmid Gigaprep KitD4204
DNA Clean & Concentrator-5D4003T / D4003 / D4013 / D4004 / D4014
DNA Clean & Concentrator-25D4033 / D4005 / D4034 / D4006
DNA Clean & Concentrator-100D4029 / D4030
ZR-96 DNA Clean & Concentrator-5 (Deep Well)D4023 / D4024
ZR-96 DNA Clean-Up KitD4017 / D4018
DNA Clean & Concentrator-500D4031 / D4032
ZymoBIOMICS DNA Miniprep KitD4300T / D4304 / D4300
ZymoBIOMICS DNA Microprep KitD4305 / D4301
ZymoBIOMICS 96 MagBead DNA KitD4306 / D4302 / D4308
ZymoBIOMICS 96 DNA KitD4307 / D4303 / D4309
Zymoclean Gel DNA Recovery KitD4001T / D4001 / D4007 / D4002 / D4008
Zymoclean Large Fragment DNA RecoveryD4045 / D4046
ZR-96 Zymoclean Gel DNA Recovery KitD4021 / D4022
Zyppy Plasmid Miniprep KitD4036 / D4019 / D4020 / D4037
Zyppy-96 Plasmid KitD4041 / D4042 / D4043
Zyppy-96 Plasmid MagBead MiniprepD4100 / D4101 / D4102
Genomic DNA Clean & Concentrator-10D4010 / D4011
Genomic DNA Clean & Concentrator-25D4064 / D4065
ZR-96 Genomic DNA Clean & Concentrator-5 KitD4066 / D4067
Quick-DNA Fecal/Soil Microbe Miniprep KitD6010
Quick-DNA Fecal/Soil Microbe MicroprepD6012
Quick-DNA Fecal/Soil Microbe 96 KitD6011
Quick-DNA Fecal/Soil Microbe 96 Magbead KitD6011-FM / D6010-FM / D6012-FM
Quick-DNA Fecal/Soil Microbe Midiprep KitD6110
Quick-DNA Fungal/Bacterial Miniprep KitD6005
Quick-DNA Fungal/Bacterial Microprep KitD6007
Quick-DNA Fungal/Bacterial 96 KitD6006
Quick-DNA Fungal/Bacterial Midiprep KitD6105
OneStep PCR Inhibitor Removal KitD6030 / D6035
Select-a-Size DNA Clean & Concentrator MagBead KitD4084 / D4085
Select-a-Size DNA Clean & Concentrator KitD4080
Quick-DNA Plant/Seed Miniprep KitD6020
Quick-DNA Plant/Seed 96 KitD6021
Quick-DNA/RNA Miniprep Plus KitD7003T / D7003
Quick-DNA/RNA Microprep Plus KitD7005T / D7005
Quick-DNA/RNA MiniprepD7001
Quick-DNA/RNA MagBeadR2130 / R2131
Zymoprep Yeast Plasmid Miniprep IID2004
Zymoprep Yeast Plasmid Miniprep ID2001
Zymoprep-96 Yeast Plasmid MiniprepD2005 / D2006 / D2007
Quick-DNA Viral KitD3015 / D3016
Quick-DNA Viral 96 KitD3017 / D3018
Quick-DNA Tissue/Insect Microprep KitD6015
Quick-DNA Tissue/Insect Miniprep KitD6016
Quick-DNA Tissue/Insect 96 KitD6017
ZR DNA Sequencing Clean-Up KitD4050 / D4051
ZR-96 DNA Sequencing Clean-up KitD4052 / D4053
Oligo Clean & ConcentratorD4060 / D4061
ZR-96 Oligo Clean & ConcentratorD4062 / D4063
Femto Bacterial DNA Quantification KitE2006
Femto Fungal DNA Quantification KitE2007
Femto Human DNA Quantification KitE2005
Direct-zol RNA Miniprep KitsR2050 / R2051 / R2052 / R2053
Direct-zol RNA Microprep KitsR2060 / R2061 / R2062 / R2063
Direct-zol RNA Miniprep Plus KitsR2070T / R2070 / R2071 / R2072 / R2073
Direct-zol-96 RNA KitsR2054 / R2055 / R2056 / R2057
Direct-zol-96 MagBead RNAR2100 / R2101 / R2102 / R2103
Direct-zol DNA/RNA MiniprepR2080T / R2080 / R2081
Quick-RNA Miniprep KitR1054 / R1055
Quick-RNA Microprep KitR1050 / R1051
Quick-RNA Miniprep Plus KitR1057T / R1057 / R1058
Quick-RNA Midiprep KitR1056
Quick-RNA 96 KitR1052 / R1053
Quick-RNA MagBeadR2132 / R2133
RNA Clean & Concentrator-5R1015 / R1013 / R1016 / R1014
RNA Clean & Concentrator-25R1017 / R1018
RNA Clean & Concentrator-100R1019
RNA Clean & Concentrator MagBeadR1081 / R1082
RNA Clean & Concentrator-96R1080
Quick-RNA Viral KitR1034 / R1034-E / R1035 / R1035-E
Quick-RNA Viral 96 KitR1040 / R1040-E / R1041 / R1041-E
Quick-RNA Fungal/Bacterial Miniprep KitR2014
Quick-RNA Fungal/Bacterial Microprep KitR2010
Quick-DNA/RNA Viral MagBeadR2140 / R2140-E / R2141 / R2141-E
Quick-DNA/RNA Viral 96 KitD7022 / D7023
Quick-DNA/RNA Viral KitD7020 / D7021
Proteinase K w/ Storage Buffer SetD3001-2-5 / D3001-2-20 / D3001-2-60 / D3001-2-125
Quick-DNA/RNA Pathogen MiniprepR1042 / R1043
Quick-DNA/RNA Pathogen MagBeadR2145 / R2146
Oligo Clean & ConcentratorD4060 / D4061
ZR-96 Oligo Clean & ConcentratorD4062 / D4063
Quick-RNA Plant KitR2024
Quick-RNA Fecal/Soil Microbe Microprep KitR2040
Quick-RNA Tissue/Insect KitR2030
Quick-RNA Whole BloodR1201
Quick-RNA FFPE MiniprepR1008
Quick-cfRNA Serum & Plasma KitR1059
ZR Urine RNA Isolation KitR1038 / R1039
Pinpoint Slide RNA Isolation SystemR1003 / R1007
Quick-DNA/RNA FFPE Miniprep KitR1009
Zymoclean Gel RNA Recovery KitR1011
ZR small-RNA  PAGE Recovery KitR1070
Oligo Clean & Concentrator KitsDNA
YeaStar RNA KitR1002
OneStep PCR Inhibitor Removal KitD6030
Zymo-Seq WGBS Library KitD5465
Pico Methyl-Seq Library Prep KitD5455 / D5456
Zymo-Seq RRBS Library KitD5460 / D5461
Zymo-Seq RiboFree Total RNA KitR3000 / R3003
Zymo-Seq RiboFree Universal cDNA KitR3001
Human Methylated & Non-methylated DNA SetD5014 / D5014-1 / D5014-2
5-mC DNA ELISA KitD5325 / D5326
OneStep qMethyl-PCR KitD5310 / D5311
Quest 5-hmC DNA ELISA KitD5425 / D5426
RRHP 5-hmC Library Prep KitD5450 / D5451
ZymoTaq PreMixE2003 / E2004
ZymoTaq DNA PolymeraseE2001 / E2002
ZymoTaq qPCR PremixE2054 / E2055
Zymo-Spin ChIP KitD5209 / D5210
ChIP DNA Clean & ConcentratorD5201 / D5205
ZR-96 ChIP DNA Clean & ConcentratorD5206 / D5207
EZ Nucleosomal DNA Prep KitD5220
dsDNA Shearase PlusE2018-200 / E2018-50
Methylated-DNA IP KitD5101
Anti-5-Methylcytosine Monoclonal Antibody (Clone 7D21)A3002-15 / A3002-200 / A3002-30 / A3002-50
Anti-5-Hydroxymethylcytosine Polyclonal AntibodyA4001-200 / A4001-25 / A4001-50
Universal Methylated DNA StandardD5011 / D5012
Bisulfite-Converted Universal Methylated Human DNA StandardD5015
Human Methylated & Non-Methylated (WGA) DNA SetD5013 / D5013-1 / D5013-2
5-Methylcytosine & 5-Hydroxymethylcytosine DNA Standard SetD5405
E. coli Non-Methylated Genomic DNAD5016
Methylated & Non-methylated pUC19 DNA SetD5017
Human Matched DNA SetD5018 / D5018-1 / D5018-2
Mouse 5-hmC & 5-mC DNA SetD5019 / D5019-1 / D5019-2 / D5019-3 / D5019-4
CpG Methylase (M. Sssl)E2010 / E2011
5-hmC GlucosyltransferaseE2026 / E2027
Atlantis dsDNaseE2030
DNA DegradaseE2016 / E2017
5-Methyl DctpD1035
5-Methylcytosine dNTP MixD1030
dNTP MixD1000-1 / D1000
dCTPD1020
dATPD1005
dTTPD1010
dGTPD1015
EZ DNA Methylation-Direct KitD5020 / D5021
EZ-96 DNA Methylation-Direct KitD5022 / D5023
EZ-96 DNA Methylation-Direct MagPrepD5044 / D5045
 EZ DNA Methylation KitD5001
 EZ DNA Methylation KitD5002
EZ-96 DNA Methylation KitD5003
EZ-97 DNA Methylation KitD5004
EZ-96 DNA Methylation MagPrepD5040
EZ-97 DNA Methylation MagPrepD5041
EZ DNA Methylation-GoldD5005
EZ DNA Methylation-GoldD5006
EZ-96 DNA Methylation-Gold KitD5007
EZ-97 DNA Methylation-Gold KitD5008
 EZ-96 DNA Methylation-Gold MagPrepD5042
 EZ-97 DNA Methylation-Gold MagPrepD5043
EZ DNA Methylation-Startup KitD5024
EZ DNA Methylation KitD5001
EZ DNA Methylation KitD5002
EZ-96 DNA Methylation KitD5003
EZ-97 DNA Methylation KitD5004
EZ-96 DNA Methylation MagPrepD5040
EZ-97 DNA Methylation MagPrepD5041
ZymoBIOMICS DNA Miniprep KitD4300T / D4304 / D4300
ZymoBIOMICS DNA Microprep KitD4305 / D4301
ZymoBIOMICS 96 MagBead DNA KitD4306 / D4302 / D4308
ZymoBIOMICS 96 DNA KitD4307 / D4303 / D4309
ZymoBIOMICS Gut Microbiome StandardD6331
ZymoBIOMICS HMW DNA StandardD6322
ZymoBIOMICS Microbial Community DNA StandardD6305 / D6306
ZymoBIOMICS Microbial Community StandardD6300
ZymoBIOMICS Spike-in Control I (High Microbial Load)D6320 / D6320-10
ZymoBIOMICS Microbial Community DNA Standard II (Log Distribution)D6311
ZymoBIOMICS Microbial Community Standard II (Log Distribution)D6310
ZymoBIOMICS Spike-in Control II (Low Microbial Load)D6321 / D6321-10
ZymoBIOMICS Fecal Reference with TruMatrix TechnologyD6323
Femto Bacterial DNA Quantification KitE2006
Femto Fungal DNA Quantification KitE2007
Femto Human DNA Quantification KitE2005
Quick-16S Plus NGS Library Prep Kit(V3-V4)D6420 / D6422
ZymoBIOMICS DNA/RNA Miniprep KitR2002
ZymoBIOMICS MagBead DNA/RNAR2135 / R2136
ZymoBIOMICS RNA Miniprep KitR2001
Mix & Go! E. coli Transformation Kit and Buffer SetT3001 / T3002
Mix & Go Competent CellsE. coli
XJ Autolysis E. coli strainsE. coli
Rattler Plating BeadsS1001 / S1001-5 / S1001-B
ZymoBrothM3015-100 / M3015-500
Dual Media SetM3011
Ampicillin Sodium SolutionA1001-25 / A1001-5
Kanamycin Sulfate SolutionA1003-25 / A1003-5
Chloramphenicol SolutionA1002-25 / A1002-5
X-GAL (5-bromo-4-chloro-3-indolyl β-D-galactopyranoside)X1001-25 / X1001-5
500x L-Arabinose SolutionA2001-1 / A2001-10
Tetracycline Hydrochloride Solution - Reagent GradeA1004-25 / A1004-5
Mix & Go! Competent Cells - DH5 AlphaT3007 / T3009 / T3010
Mix & Go! Competent Cells-JM109T3003 / T3005
Mix & Go! XJb (DE3) Autolysis Competent CellsT3051
Mix & Go! Competent Cells-Zymo 10BT3019 / T3020
Mix & Go! Competent Cells-TG1T3017
Mix & Go! Competent Cells-HB101T3011 / T3013
Mix & Go! XJa (DE3) Autolysis Competent CellsT3031
Mix & Go! XJb Autolysis Competent CellsT3041
Mix & Go! XJa Autolysis Competent CellsT3021
Mix & Go! XJb (DE3) Autolysis Competent CellsT3051
XJb (DE3) Autolysis Glycerol StockT5051
Mix & Go! XJa (DE3) Autolysis Competent CellsT3031
Mix & Go! XJb Autolysis Competent CellsT3041
XJb Autolysis Glycerol StockT5041
XJa (DE3) Autolysis Glycerol StockT5031
XJa Autolysis Glycerol StockT5021
Mix & Go! XJa Autolysis Competent CellsT3021
Zymoprep Yeast Plasmid Miniprep KitsYeast
Quick-DNA Fungal/Bacterial KitsDNA
ZymolyaseE1004 / E1005 / E1006
5-Fluoroorotic Acid (5-FOA)F9001-1 / F9001-5 / F9003
YeaStar RNA KitR1002
Frozen-EZ Yeast Transformation II KitT2001
Frozen-EZ Yeast SolutionT2002 / T2003 / T2004
YeaStar Genomic DNA KitD2002
YPD PlusY1003-100 / Y1003-50
Zymoprep Yeast Plasmid Miniprep ID2001
Zymoprep Yeast Plasmid Miniprep IID2004
Zymoprep-96 Yeast Plasmid MiniprepD2007
Quick-DNA Fungal/Bacterial Microprep KitD6007
Quick-DNA Fungal/Bacterial Miniprep KitD6005
Quick-DNA Fungal/Bacterial Midiprep KitD6105
Quick-DNA Fungal/Bacterial 96 KitD6006
Zymoprep Yeast Plasmid Miniprep ID2001
Zymoprep Yeast Plasmid Miniprep IID2004
Zymoprep-96 Yeast Plasmid MiniprepD2007
Quick-DNA Fungal/Bacterial Microprep KitD6007
Quick-DNA Fungal/Bacterial Miniprep KitD6005
Quick-DNA Fungal/Bacterial Midiprep KitD6105
Quick-DNA Fungal/Bacterial 96 KitD6006
XJ Autolysis E. coli strainsE. coli
His-Spin Protein MiniprepP2001 / P2002
Yeast Protein KitY1002
Strep-Spin Protein Miniprep KitP2004 / P2005
ZymolyaseE1004 / E1005 / E1006
DNase I SetE1010
ZymoTaq PolymeraseBuffers
DNA Degradase PlusE2020 / E2021
MBP-Spin Protein Miniprep KitP2006 / P2007
Dual Media SetM3011
dsDNA Shearase PlusE2018-200 / E2018-50
RNase AE1008-24 / E1008-30 / E1008-8
CpG Methylase (M. Sssl)E2010 / E2011
Atlantis dsDNaseE2030
Proteinase K w/ Storage Buffer SetD3001-2-20 / D3001-2-5
5-hmC GlucosyltransferaseE2026 / E2027
Micrococcal NucleaseD5220-1
DNA DegradaseE2016 / E2017
Mix & Go! XJb (DE3) Autolysis Competent CellsT3051
XJb (DE3) Autolysis Glycerol StockT5051
Mix & Go! XJa (DE3) Autolysis Competent CellsT3031
Mix & Go! XJb Autolysis Competent CellsT3041
XJb Autolysis Glycerol StockT5041
XJa (DE3) Autolysis Glycerol StockT5031
XJa Autolysis Glycerol StockT5021
Mix & Go! XJa Autolysis Competent CellsT3021
ZymoTaq PreMixE2003 / E2004
ZymoTaq DNA PolymeraseE2001 / E2002
ZymoTaq qPCR PremixE2054 / E2055


更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

" data-original="http://gerbu.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Zymo Research全系列产品,现货销售">
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Affinity Biologicals.jpg


艾美捷科技有限公司代理Affinity Biologicals公司产品,如下:


(1)Matched-Pair Antibody Sets

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/1.html

(2)Factor Inhibitor Plasmas

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/2.html

(3)Control Plasma-Diagnostic

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/2.html

(4)Deficient Plasmas

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/3.html

(5)Complete ELISA Kit

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/5.html

(6)Antibodies

http://www.amyjet.com/Index/lists/catid/27/kid/52/p/6.html


Affinity Biologicals公司成立于1987年,提供包括凝血相关抗体、ELISA试剂盒、无蛋白酶抑制剂血浆和校准血浆等系列产品。Affinity Biologicals还提供蛋白纯化、抗体生产、检测方法开发、定制生产等服务。

 

Affinity Biologicals, Inc. is a primary manufacturer of products used worldwide in thrombosis and hemostasis research and medical diagnostics. Our products include an extensive line of antibodies to coagulation and hemostasis related proteins, conjugates, antibody pairs for immunoassay of human and animal analytes, the VisuLize line of complete ELISA kits, and a full line of human plasma products including immune-depleted plasmas, calibrators and controls. Custom Services include protein purification, antibody production, assay development, custom manufacturing and lyophilization.

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Affinity Biologicals
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ClearsynthPNG.png

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艾美捷科技代理Clearsynth品牌全系列产品


Clearsynth研发中心位于海得拉巴,以“创新与精准之心”为核心理念,打造了一个精心设计的空间,旨在激发突破性的发现并提升可能性的界限。专注于创新有机化学和独特复杂分子的合成,涵盖稳定同位素标记化合物、代谢物、杂质、葡萄糖醛酸、手性化合物、共轭物杂质和放射性标记化合物等。承接复杂分子或“难以合成”的合成化合物/中间体的定制合成服务。提供超过3,59,000个高纯度参考标准品,Clearsynth公司的产品线包括稳定同位素、原料药、杂质、亚硝胺、二级标准、散装化合物等。


Clearsynth页面.png


Clearsynth服务领域

● 小分子:合成各种精细化学品和化合物,用于从毫克到数公斤规模的小分子药物发现。

● 工艺开发:开发新的合成路线,也可以修改和优化客户提供的工艺。

● 合同研发综合:专注于从临床前阶段到III期以及成功的技术转让。

● 生物核磁共振服务:位于海得拉巴的符合GLP标准的高场生物核磁共振/600MHz和300MHz设施,由敬业且经验丰富的核磁共振操作员提供支持。

● CDMO服务:致力于复杂、危险和可持续的产品和工艺。

● 分析服务:符合FDA、BIS、卫生部和其他标准机构制定的所有监管规范。


Clearsynth部分产品列表


品名货号CAS号
α-Keto Isovaleric Acid Sodium Salt 13C D6CS-R-005623715-29-5 (Unlabeled)
α-Keto Isovaleric Acid Sodium Salt 13C5CS-R-004821173018-24-0
α-Keto Isovaleric Acid Sodium Salt D6CS-R-004853715-29-5(Unlabeled)
α-Keto Isovaleric Acid Sodium Salt Dimethyl-13C2CS-R-00488634908-42-2
α-KETOBUTYRIC ACID, SODIUM 13C, D4CS-R-004752013-26-5 (Unlabeled)
α-KETOBUTYRIC ACID, SODIUM SALT 13C4, D2CS-R-00477360769-17-1
α-KETOBUTYRIC ACID, SODIUM SALT METHYL-13CCS-R-00478634908-43-3
α-KETOBUTYRIC ACID, SODIUM SALT METHYL-13C, D2CS-R-004791007476-77-8
α-Ketobutyric Acid-d2 Sodium SaltCS-T-302941007476-82-5
α-Ketoglutaric acid 13C2, D2CS-CX-00331123953-28-6
α-KETOGLUTARIC ACID 13C5CS-R-00549161096-83-9
α-KETOGLUTARIC ACID, DISODIUM SALT 13C4CS-R-004801429051-79-5
α-KETOISOCAPROIC ACID 13CCS-R-0055192751-19-4
α-KETOISOCAPROIC ACID, SODIUM SALT 13C2CS-R-005524502-00-5(Unlabeled)
α-KETOISOCAPROIC ACID, SODIUM SALT ISOPROPYL-D7CS-R-005551795020-84-6
α-Tocopherol-[13C3]CS-I-0034059-02-9 (Unlabeled)
β-ALANINE 13CCS-R-0004265138-34-3
β-ALANINE 13C, 15NCS-R-004491822942-84-6
β-ALANINE 13C3CS-R-00040107-95-9 (Unlabeled)
β-ALANINE 15NCS-R-00041204451-53-6
β-CAROTENE 13C4CS-R-005677235-40-7(Unlabeled)
-β-Cyclocitral-d5CS-T-5141078995-98-9
β-Endosulfan D4CS-O-15034203716-99-8
β-Ionone-[13C3]CS-I-0036814901-07-6 (Unlabeled)
βmethasone 17-propionate-d3CS-O-104265534-13-4 (Unlabeled)
β-Tocopherol-[13C9]CS-I-0034159-02-9 (Unlabeled)
γ-HCH D6CS-EJ-000960556-82-3
(-)-(2S,3S)-Viridifloric Acid Acetonide-d7CS-T-10281695462-09-2(Unlabelled)
(-)-(2S,3S)-Viridifloric Acid Ethyl Ester-d7CS-T-102815176712-53-1(Unlabelled)
(-)-(3S)-3-Hydroxy Quinine-vinyl-d3CS-T-1012622734920-65-9
(-)-(S)-Cibenzoline-D4CS-O-33254103419-18-7 (Unlabeled)
(-)-2-Amino-6-propionamido-d3-tetrahydrobenzothiazoleCS-T-978051217644-20-6
(-)-2-Methyl Isoborneol-d3CS-T-58298135441-89-3
(-)-alfa-Benidipine-d5 HydrochlorideCS-P-07295129262-07-3 (Unlabeled)
(-)-Cannabidiol-d9CS-TA-863221246819-21-5
(-)-Citrinin-13C,d2CS-T-728771329611-85-9


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艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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